| Course Unit Code | Course Unit Title | Type of Course Unit | Year of Study | Semester | Number of ECTS Credits | | GIM-23-105 | | Elective | 1 | 2 | 6 |
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| Level of Course Unit |
| Second Cycle |
| Objectives of the Course |
| The course aims to provide insight into proteins at the molecular level, to teach experimental and computational protein structure solving techniques, and analysis of structures to understand the structure-function relationship of proteins. |
| Name of Lecturer(s) |
| Doç. Dr. Gülçin YILDIZ |
| Learning Outcomes |
| 1 | To understand genetic code and protein synthesis | | 2 | To understand protein structure-function relationship | | 3 | To learn bioinformatic and computational tools to analyze, visualize and modify protein structure |
|
| Mode of Delivery |
| Daytime Class |
| Prerequisites and co-requisities |
| none |
| Recommended Optional Programme Components |
| none |
| Course Contents |
| Protein synthesis and amino acids
Protein folding, secondary and tertiary structure
Protein motifs
Protein structure-function relationship
Computational methods and bioinformatic tools in understanding protein structure and
function
Experimental structure determination using X-ray methods, NMR and other methods
Protein-protein interaction and function regulation
Structural Microbiology |
| Weekly Detailed Course Contents |
|
| 1 | Introduction to the course | | | | 2 | definition of molecular structure | | | | 3 | Introduction to databases and literature search | | | | 4 | Central Dogma; DNA replication | | | | 5 | Central Dogma; DNA replication | | | | 6 | Genetic code and Protein Synthesis | | | | 7 | Amino acids, Peptide Bond and Secondary Structure | | | | 8 | Tertiary Structure I: Fold types | | | | 9 | Tertiary Structure II: Thermodynamics of Protein Folding | | | | 10 | Structure-Function Relationship | | | | 11 | Structure-Function Relationship | | | | 12 | Peptide and Protein Structure Modeling and Analysis Part 1- Bioactive Peptides | | | | 13 | Peptide and Protein Structure Modeling and Analysis Part 1- Bioactive Peptides | | | | 14 | Peptide and Protein Structure Modeling and Analysis Part 2- Structural modeling | | |
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| Recommended or Required Reading |
| Gregory A. Petsko, Dagmar Ringe, Protein Structure and Function, New Science Press, 2004 |
| Planned Learning Activities and Teaching Methods |
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| Assessment Methods and Criteria | |
| Midterm Examination | 1 | 100 | | SUM | 100 | |
| Final Examination | 1 | 100 | | SUM | 100 | | Term (or Year) Learning Activities | 50 | | End Of Term (or Year) Learning Activities | 50 | | SUM | 100 |
| | Language of Instruction | | | Work Placement(s) | | none |
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| Workload Calculation |
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| Midterm Examination | 1 | 1 | 1 |
| Final Examination | 1 | 1 | 1 |
| Self Study | 1 | 25 | 25 |
| Individual Study for Mid term Examination | 1 | 50 | 50 |
| Individual Study for Final Examination | 1 | 50 | 50 |
| Homework | 1 | 50 | 50 |
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| Contribution of Learning Outcomes to Programme Outcomes |
| LO1 | 3 | 5 | 4 | 5 | 4 | 5 | 4 | 5 | 4 | 5 | 5 | 4 | 5 | 4 | 5 | 4 | | LO2 | 4 | 4 | 5 | 3 | 5 | 5 | 5 | 4 | 4 | 3 | 5 | 4 | 5 | 4 | 4 | 4 | | LO3 | 4 | 5 | 4 | 4 | 3 | 5 | 4 | 5 | 4 | 4 | 5 | 5 | 5 | 5 | 5 | 5 |
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| * Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High |
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Iğdır University, Iğdır / TURKEY • Tel (pbx): +90 476
226 13 14 • e-mail: info@igdir.edu.tr
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