Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
BYK-23-102İLERİ BİYOORGANİK KİMYAElective116
Level of Course Unit
Second Cycle
Objectives of the Course
Biochemistry is widely used today. Diagnostic methods related to biochemical analyzes that provide the most information in the field of medicine support the treatment. In the West, intensive scientific studies have been started in the field of Bioorganic Chemistry and very important results are obtained. One of the most important results is that the environmental conditions can be obtained in a short time by analyzing the biological and organic materials together. Information on the objectives of the use of the Bioorganic Chemistry course, which has such a wide range of applications, must be provided to doctoral students who conduct advanced research.
Name of Lecturer(s)
Prof. Dr. İbrahim DEMİRTAŞ
Learning Outcomes
11-Understand the basic concepts and principles of Bioorganic Chemistry
22-Makes comments about reaction mechanisms
33-Recognizes the organic compounds used in daily life
44-Solves organic chemistry and biochemistry problems
Mode of Delivery
Daytime Class
Prerequisites and co-requisities
none
Recommended Optional Programme Components
1-Understand the basic concepts and principles of Bioorganic Chemistry 2-Makes comments about reaction mechanisms 3-Recognizes the organic compounds used in daily life 4-Solves organic chemistry and biochemistry problems
Course Contents
Biochemistry is widely used today. Diagnostic methods related to biochemical analyzes that provide the most information in the field of medicine support the treatment. In the West, intensive scientific studies have been started in the field of Bioorganic Chemistry and very important results are obtained. One of the most important results is that the environmental conditions can be obtained in a short time by analyzing the biological and organic materials together. Information on the objectives of the use of the Bioorganic Chemistry course, which has such a wide range of applications, must be provided to doctoral students who conduct advanced research. Carbon Compounds and Chemical Bonds, Introduction to Organic Reactions- Basic Organic Reactions and Mechanisms, Hydrocarbons: Alkanes and Cycloalkanes, Hydrocarbons: Alkanes and Cycloalkanes, Stereochemistry, Stereochemistry, Alkyl Halogenides: Nucleophilic Displacement and Separation Reactions, Hydrocarbons; Alkanes. Common topics of Biochemistry and Organic Chemistry
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Carbon compounds and chemical bonds Covalent bonds, orbital hybridization, fonctional groups,IUPAC nomenclature of organic structures
2Organic reactions and the mechanisms:substitution addition,elimination,rearrangement reactions,acid and bases in organic chemistry
3Alkanes and cycloalkanes:molecular formula,nomenclature,pyhsıcal properties and reactions.
4Alkanes and cycloalkanes:conformational analysis,cis and trans isomerism,bicyclic alkanes
5Stereochemistry:constitutional isomerism,enantiomers,biologic importance,optical activity,racemic mixtures.
6Stereochemistry:chiral compounds with more than one stereocenters,Fischer projection formulas.
7Alkyl halides: Nucleophilic sustitution and elimination reactons,nomenclature,mechanism of SN1 and SN2, molecular rearrangements.
8Alkyl halides:Factor afffecting the rates of SN1 and SN2 reactions and fonctional group transformations.
9Alkyl halides:Nucleophilic Sunstitution and elimination reactions:elimination reactions of alkyl halides,E1 and E2 reactions,substitıtion versus elimination
10Hydrocarbons:alkens:nomenclature,physical properties,hydrogenation,carbocation stability,alkenes addition reactions,markovnikov rule.
11Hydrocarbons:alkenes:addition of water and sulphuric acid to alkenes,hydroboration-oxidation,halogen addition,halohydrin formation
12Hydrocarbons.alkenes:epoxidation,hydrolysis of epoxides,anti-hydroxilation,alkene oxidations.
13Hydrocarbons:alkynes:alkyne reaction, Hydrocarbons:alkynes:alkyne reactions,hydrogen,halogen ,HX,water additions,hydroborations-oxidations,acity or terminal alkynes,oxidation of alkynes.
14Common uses of Biochemistry and Organic Chemistry
Recommended or Required Reading
Schmuck, C., & Wennemers, H. (2004). Highlights in bioorganic chemistry. Wiley-VCH Verlag GmbH & Co.: Weinheim. Dugas, H., & Penney, C. (2013). Bioorganic chemistry: a chemical approach to enzyme action. Springer Science & Business Media.
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
Midterm Examination1100
SUM100
End Of Term (or Year) Learning ActivitiesQuantityWeight
Final Examination1100
SUM100
Term (or Year) Learning Activities50
End Of Term (or Year) Learning Activities50
SUM100
Language of Instruction
Work Placement(s)
none
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Final Examination111
Makeup Examination122
Attending Lectures14342
Brain Storming14342
Self Study14570
Individual Study for Mid term Examination12020
Individual Study for Final Examination111
Homework111
TOTAL WORKLOAD (hours)179
Contribution of Learning Outcomes to Programme Outcomes
PO
1
PO
2
PO
3
PO
4
LO145  
LO2455 
LO35   
LO42   
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
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