Course Unit Code | Course Unit Title | Type of Course Unit | Year of Study | Semester | Number of ECTS Credits | 180300905101 | BIOINORGANIC CHEMISTRY | Compulsory | 3 | 5 | 3 |
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Level of Course Unit |
First Cycle |
Objectives of the Course |
The objective of this course is to provide an understanding of the role of inorganic components in biological systems. The course emphasizes the functions of metal ions in biological systems and the applications of bioinorganic chemistry in medicine, biotechnology, and environmental sciences. |
Name of Lecturer(s) |
DOÇ. DR. TUĞBA BAYRAKTUTAN |
Learning Outcomes |
1 | Understand the functions of metal ions in biological systems. | 2 | Describe the structure and functions of metalloenzymes. | 3 | Evaluate metal-biomolecule interactions. | 4 | Understand the chemical structure and effects of metal-based drugs. | 5 | Analyze the applications of bioinorganic chemistry in fields such as biotechnology and medicine. |
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Mode of Delivery |
Daytime Class |
Prerequisites and co-requisities |
none |
Recommended Optional Programme Components |
none |
Course Contents |
Theoretical lectures
Article reviews and presentations
Group discussions |
Weekly Detailed Course Contents |
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1 | Introduction to bioinorganic chemistry | | | 2 | Biological roles of metal ions | | | 3 | Natural and artificial metalloenzymes | | | 4 | Functions of Metals in Biological Systems | | | 5 | Oxygen transport and storage (hemoglobin, myoglobin) | | | 6 | Photosynthesis and chlorophyll | | | 7 | Metal-based enzymes (carbonic anhydrase, nitrogenase, superoxide dismutase) | | | 8 | Toxicity of metal ions and biological defense mechanisms | | | 9 | Cellular transport of metal ions | | | 10 | Metal-based drugs (cisplatin and its derivatives) | | | 11 | Radiopharmaceuticals | | | 12 | Environmental and industrial impacts of metal ions | | | 13 | Biomimetic complexes | | | 14 | Artificial metalloenzymes | | |
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Recommended or Required Reading |
Bertini, I., Gray, H. B., Stiefel, E. I., & Valentine, J. S. Biological Inorganic Chemistry: Structure and Reactivity.
Lippard, S. J., & Berg, J. M. Principles of Bioinorganic Chemistry.
Fraústo da Silva, J. J. R., & Williams, R. J. P. The Biological Chemistry of the Elements. |
Planned Learning Activities and Teaching Methods |
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Assessment Methods and Criteria | |
Midterm Examination | 1 | 100 | SUM | 100 | |
Final Examination | 1 | 100 | SUM | 100 | Term (or Year) Learning Activities | 40 | End Of Term (or Year) Learning Activities | 60 | SUM | 100 |
| Language of Instruction | | Work Placement(s) | none |
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Workload Calculation |
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Midterm Examination | 1 | 1 | 1 |
Final Examination | 1 | 2 | 2 |
Makeup Examination | 1 | 10 | 10 |
Attending Lectures | 14 | 3 | 42 |
Discussion | 3 | 1 | 3 |
Question-Answer | 3 | 1 | 3 |
Individual Study for Mid term Examination | 1 | 10 | 10 |
Individual Study for Final Examination | 1 | 17 | 17 |
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Contribution of Learning Outcomes to Programme Outcomes |
LO1 | | | | | | | | 3 | | | | | | | | LO2 | | | | | | | | | | 5 | | | | | | LO3 | | | | | | | | | | 3 | | | | | | LO4 | | | | | | | | | | 4 | | | | | | LO5 | | | | | | | | 5 | | | | | | | |
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* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High |
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Iğdır University, Iğdır / TURKEY • Tel (pbx): +90 476
226 13 14 • e-mail: info@igdir.edu.tr
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