Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
180300905101BIOINORGANIC CHEMISTRYCompulsory353
Level of Course Unit
First Cycle
Objectives of the Course
The objective of this course is to provide an understanding of the role of inorganic components in biological systems. The course emphasizes the functions of metal ions in biological systems and the applications of bioinorganic chemistry in medicine, biotechnology, and environmental sciences.
Name of Lecturer(s)
DOÇ. DR. TUĞBA BAYRAKTUTAN
Learning Outcomes
1Understand the functions of metal ions in biological systems.
2Describe the structure and functions of metalloenzymes.
3Evaluate metal-biomolecule interactions.
4Understand the chemical structure and effects of metal-based drugs.
5Analyze the applications of bioinorganic chemistry in fields such as biotechnology and medicine.
Mode of Delivery
Daytime Class
Prerequisites and co-requisities
none
Recommended Optional Programme Components
none
Course Contents
Theoretical lectures Article reviews and presentations Group discussions
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Introduction to bioinorganic chemistry
2Biological roles of metal ions
3Natural and artificial metalloenzymes
4Functions of Metals in Biological Systems
5Oxygen transport and storage (hemoglobin, myoglobin)
6Photosynthesis and chlorophyll
7Metal-based enzymes (carbonic anhydrase, nitrogenase, superoxide dismutase)
8Toxicity of metal ions and biological defense mechanisms
9Cellular transport of metal ions
10Metal-based drugs (cisplatin and its derivatives)
11Radiopharmaceuticals
12Environmental and industrial impacts of metal ions
13Biomimetic complexes
14Artificial metalloenzymes
Recommended or Required Reading
Bertini, I., Gray, H. B., Stiefel, E. I., & Valentine, J. S. Biological Inorganic Chemistry: Structure and Reactivity. Lippard, S. J., & Berg, J. M. Principles of Bioinorganic Chemistry. Fraústo da Silva, J. J. R., & Williams, R. J. P. The Biological Chemistry of the Elements.
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
Midterm Examination1100
SUM100
End Of Term (or Year) Learning ActivitiesQuantityWeight
Final Examination1100
SUM100
Term (or Year) Learning Activities40
End Of Term (or Year) Learning Activities60
SUM100
Language of Instruction
Work Placement(s)
none
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination111
Final Examination122
Makeup Examination11010
Attending Lectures14342
Discussion313
Question-Answer313
Individual Study for Mid term Examination11010
Individual Study for Final Examination11717
TOTAL WORKLOAD (hours)88
Contribution of Learning Outcomes to Programme Outcomes
PO
1
PO
2
PO
3
PO
4
PO
5
PO
6
PO
7
PO
8
PO
9
PO
10
PO
11
PO
12
PO
13
PO
14
PO
15
LO1       3       
LO2         5     
LO3         3     
LO4         4     
LO5       5       
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
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