Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
GIM-23-106ENZIM KINETIĞIElective126
Level of Course Unit
Second Cycle
Objectives of the Course
To teach the basic lines of enzyme kinetics To teach the structure, function, activity determination, inhibition and activation kinetics of enzymes for enzyme research.
Name of Lecturer(s)
Dr. Öğr. Üyesi Uğur GÜLLER
Learning Outcomes
11) Students are able to learn basic concepts of enzymes. 2) Students are able to learn the concepts of enzyme inhibition. 3) Students are able to learn graphs and equations related to enzyme kinetics. 4) Students are able to learn allosteric enzyme inhibition and kinetics. 5) Students are able to learn the types of enzyme inhibition.
Mode of Delivery
Daytime Class
Prerequisites and co-requisities
none
Recommended Optional Programme Components
Course Contents
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1General information about proteins
2Enzymes, general properties and purification criteria
3Classification of enzymes
4Enzyme cofactors
5Coenzymes and enzyme active site
6Enzyme inhibition-Michaelis Menten graph and obtaining the equation
7Importance of KM and Vmax expressions
8Enzyme inhibition-Eadie Hofstee graph, obtaining the equation, and interpretation
9Wolf transformation
10Kinetics of multi-substrate enzymatic reactions
11Sterospecificity of enzymes and catalysis mechanism
12Factors affecting enzyme activity
13Multienzyme systems
14Allosteric enzyme kinetics and inhibition
Recommended or Required Reading
1) Biyokimya, E.Edip Keha ve Ö.İrfan Küfrevioğlu, Aktif Yayınevi, Erzurum, 2010. 2) Biyokimyanın İlkeleri, Albert L.Lehninger, David L.Nelson and Michael M.Cox, Second Edition, Worth Publishers, New York, 1993. 3) Biyokimya (Harper) Robert K. Murray, Daryl K. Granner, Peter A. Mayes, Victor W. Rodwell,Nobel Tıp Kitabevi, 2004. 4) Biyokimya , Pamela C. Champe, Richard A. Harvey, Denise R. Ferrier, Nobel Tıp Kitabevi,2007
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
Midterm Examination1100
SUM100
End Of Term (or Year) Learning ActivitiesQuantityWeight
Final Examination1100
SUM100
Term (or Year) Learning Activities50
End Of Term (or Year) Learning Activities50
SUM100
Language of Instruction
Turkish
Work Placement(s)
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination111
Final Examination122
Attending Lectures14342
Laboratory166
Problem Solving11212
Discussion11212
Experiment166
Brain Storming166
Report Preparation11212
Report Presentation133
Project Preparation11212
Project Presentation166
Seminar11212
Criticising Paper11212
Self Study11212
Report11212
Homework11212
TOTAL WORKLOAD (hours)180
Contribution of Learning Outcomes to Programme Outcomes
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1
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2
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3
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4
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5
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6
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7
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8
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9
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10
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11
PO
12
PO
13
PO
14
PO
15
PO
16
LO14445455544444455
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
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