Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
BYK-23-113Elective126
Level of Course Unit
Second Cycle
Objectives of the Course
This course introduces students to the concepts and skills necessary to understand the behavior of molecular systems in the biological and chemical sciences at a quantitative level, through the formalisms of classical and statistical thermodynamics.
Name of Lecturer(s)
Doç. Dr. Tuğba bayraktutan
Learning Outcomes
11. It introduces some fundamental concepts relating to system, surroundings , equilibrium, and reversibility.
22. It introduces the second law and entropy.
33. It takes the idea of the entropy as a thermodynamic potential for an isolated system and transforms it into potentials for nonisolated systems.
44. It uses the concept of chemical potential to discuss phase equilibrium in simple systems.
55. It applies the reaction thermodynamics to a fundamental process in biology.
Mode of Delivery
Daytime Class
Prerequisites and co-requisities
none
Recommended Optional Programme Components
1. It introduces some fundamental concepts relating to system, surroundings , equilibrium, and reversibility. 2. It introduces the second law and entropy. 3. It takes the idea of the entropy as a thermodynamic potential for an isolated system and transforms it into potentials for nonisolated systems. 4. It uses the concept of chemical potential to discuss phase equilibrium in simple systems. 5. It applies the reaction thermodynamics to a fundamental process in biology.
Course Contents
This course goals; provide a deep and intuitive understanding of the ideas and equations of thermodynamics, and provide the computational and statistical skills to analyze data using the thermodynamic framework. To achieve the first goal, I have developed a presentation that I hope is both intuitive and rigorous. In my experience, many of the great texts in physical chemistry, both at the undergraduate and graduate level
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1Equilibrium, Changes Of State, And Reversibility
2Heat, Work
3Reversible Processes and Irreversible Processes
4Entropy Calculations, Entropy Changes, Fractional Populations
5Internal Energy
6The Gibbs–Duhem Relationship
7Using Chemical Potentials to Describe Phase Transitions
8Conformational Equilibrium
9Statistical Thermodynamics and the Ensemble Method
10Ensembles That Interact with Their Surroundings
11Partition Functions for Single Molecules and Chemical Reactions
12The Helix–Coil Transition
13Ligand Binding Equilibria from a Macroscopic Perspective
14Ligand Binding Equilibria from a Microscopic Perspective
Recommended or Required Reading
1. Biomolecular Thermodynamics_ From Theory to Application- Douglas Barrick - Taylor & Francis_CRC Press (2017) 2. Entropy and Free Energy in Structural Biology-Hagai Meirovitch- CRC Press 2020
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
Midterm Examination1100
SUM100
End Of Term (or Year) Learning ActivitiesQuantityWeight
Final Examination1100
SUM100
Term (or Year) Learning Activities50
End Of Term (or Year) Learning Activities50
SUM100
Language of Instruction
Work Placement(s)
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination111
Final Examination111
Makeup Examination11515
Attending Lectures14114
Question-Answer14114
Brain Storming14114
Seminar11515
Self Study14570
Individual Study for Mid term Examination12020
Individual Study for Final Examination11515
TOTAL WORKLOAD (hours)179
Contribution of Learning Outcomes to Programme Outcomes
PO
1
PO
2
PO
3
PO
4
LO15   
LO2 5  
LO3  5 
LO4   5
LO5   4
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
Iğdır University, Iğdır / TURKEY • Tel (pbx): +90 476 226 13 14 • e-mail: info@igdir.edu.tr