Course Unit Code | Course Unit Title | Type of Course Unit | Year of Study | Semester | Number of ECTS Credits | BYK-23-113 | | Elective | 1 | 2 | 6 |
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Level of Course Unit |
Second Cycle |
Objectives of the Course |
This course introduces students to the concepts and skills necessary to understand the behavior of molecular systems in the biological and chemical sciences at a quantitative level, through the formalisms of classical and statistical thermodynamics. |
Name of Lecturer(s) |
Doç. Dr. Tuğba bayraktutan |
Learning Outcomes |
1 | 1. It introduces some fundamental concepts relating to system, surroundings , equilibrium, and reversibility. | 2 | 2. It introduces the second law and entropy. | 3 | 3. It takes the idea of the entropy as a thermodynamic potential for an isolated system and transforms it into potentials for nonisolated systems. | 4 | 4. It uses the concept of chemical potential to discuss phase equilibrium in simple systems. | 5 | 5. It applies the reaction thermodynamics to a fundamental process in biology. |
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Mode of Delivery |
Daytime Class |
Prerequisites and co-requisities |
none |
Recommended Optional Programme Components |
1. It introduces some fundamental concepts relating to system, surroundings , equilibrium, and reversibility.
2. It introduces the second law and entropy.
3. It takes the idea of the entropy as a thermodynamic potential for an isolated system and transforms it into potentials for nonisolated systems.
4. It uses the concept of chemical potential to discuss phase equilibrium in simple systems.
5. It applies the reaction thermodynamics to a fundamental process in biology. |
Course Contents |
This course goals; provide a deep and intuitive understanding of the ideas and equations of thermodynamics, and provide the computational and statistical skills to analyze data using the thermodynamic framework. To achieve the first goal, I have developed a presentation that I hope is both intuitive and rigorous.
In my experience, many of the great texts in physical chemistry, both at the undergraduate and graduate level |
Weekly Detailed Course Contents |
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1 | Equilibrium, Changes Of State, And Reversibility | | | 2 | Heat, Work | | | 3 | Reversible Processes and Irreversible Processes | | | 4 | Entropy Calculations, Entropy Changes, Fractional Populations | | | 5 | Internal Energy | | | 6 | The Gibbs–Duhem Relationship | | | 7 | Using Chemical Potentials to Describe Phase Transitions | | | 8 | Conformational Equilibrium | | | 9 | Statistical Thermodynamics and the Ensemble Method | | | 10 | Ensembles That Interact with Their Surroundings | | | 11 | Partition Functions for Single Molecules and Chemical Reactions | | | 12 | The Helix–Coil Transition | | | 13 | Ligand Binding Equilibria from a Macroscopic Perspective | | | 14 | Ligand Binding Equilibria from a Microscopic Perspective | | |
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Recommended or Required Reading |
1. Biomolecular Thermodynamics_ From Theory to Application- Douglas Barrick - Taylor & Francis_CRC Press (2017)
2. Entropy and Free Energy in Structural Biology-Hagai Meirovitch- CRC Press 2020 |
Planned Learning Activities and Teaching Methods |
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Assessment Methods and Criteria | |
Midterm Examination | 1 | 100 | SUM | 100 | |
Final Examination | 1 | 100 | SUM | 100 | Term (or Year) Learning Activities | 50 | End Of Term (or Year) Learning Activities | 50 | SUM | 100 |
| Language of Instruction | | Work Placement(s) | |
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Workload Calculation |
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Midterm Examination | 1 | 1 | 1 |
Final Examination | 1 | 1 | 1 |
Makeup Examination | 1 | 15 | 15 |
Attending Lectures | 14 | 1 | 14 |
Question-Answer | 14 | 1 | 14 |
Brain Storming | 14 | 1 | 14 |
Seminar | 1 | 15 | 15 |
Self Study | 14 | 5 | 70 |
Individual Study for Mid term Examination | 1 | 20 | 20 |
Individual Study for Final Examination | 1 | 15 | 15 |
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Contribution of Learning Outcomes to Programme Outcomes |
LO1 | 5 | | | | LO2 | | 5 | | | LO3 | | | 5 | | LO4 | | | | 5 | LO5 | | | | 4 |
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* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High |
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Iğdır University, Iğdır / TURKEY • Tel (pbx): +90 476
226 13 14 • e-mail: info@igdir.edu.tr
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