Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
MTM-23-102DESIGN PRINCIPLES OF BIOMATERIALSElective116
Level of Course Unit
Second Cycle
Objectives of the Course
1-The structure, biomechanics, physical properties of hard and soft tissues. Physiological forces. 2-Aspects of bone formation, healing, resorption and its behavior under mechanical stimuli. 3-Implant/prosthesis interface and its importance in implant / prosthesis design. 4-Implant / prosthesis materials and their forms, biocompatibility. Implant / Prosthesis systems.
Name of Lecturer(s)
Doktor Öğretim Üyesi Gökçen AKGÜN
Learning Outcomes
11-The structure and properties of hard and soft tissues and the level of biological forces. 2-Post implantation, bone formation, healing, resorption mechanics and the effect of loading on these mechanisms. 3-Implant / prosthesis interface and its importance in implant / prosthesis design. 4-The concept of biocompatibility and Assumptions and its importance in implant/ prosthesis design. 5-Types and properties of implant / prosthesis materials and their forms. 6-Types and applications of implant / prosthesis systems.
Mode of Delivery
Daytime Class
Prerequisites and co-requisities
Recommended Optional Programme Components
Course Contents
The structure and types of hard and soft tissues. Post-implantation bone formation, modeling and healing mechanisms. Concepts of bone adaptation, osseointegration, micro motion, stress shielding and bone resorption. Tissue / Biomaterial interface, stress transfer in between. The biomechanical properties of tissues and biological forces. Aspects of Biocompatibility. Materials and forms used in implants and Prosthesis. Fracture fixation devices, implants and artificial prosthesis systems.
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1The types and structure of hard and soft tissues. Their structure property relations.
2Post implantation bone formation, modeling / remodeling and resorption mechanisms.
3Mechanically mediated bone adaptation, osseointegration, micro-motion, stress shielding and bone resorption concepts
4Tissue adaptation in response to mechanical stimulus and healing mechanisms.
5Implant / biomaterials interface; cement fixation, porous ingrowth, mechanical locking, direct bonding between bone and implant, interface and passive fixation.
6Stress transfer between tissue and biomaterial.
7Mechanical properties of soft and hard tissues and biological forces.
8İmplant / prosthesis materials (Metals, ceramics polymers and composites) and their forms (dense forms, porous materials, scaffolds, grafts, composites, coatings, and nano-structured forms) Aspects of biocompatibility
9
10Fracture fixation devices; internal fixation devices, external fixators (ilizarow), intermedullary rods, harrington rods.
11Dental and Orthopedic Implant Types, Prostheses Soft tissue replacements.
12Basic Principles of Orthosis
13Case studies
14
Recommended or Required Reading
‘’Biomaterials principles and practices’’, 2013. Joyce Y.WONG Joseph, d.bronzino, Donald, R. Peterson. Biomaterials An Introduction, J. Park, ,Springer, 1st edition, 2010. Hydroxyapatite Synthesis, Properties and Applications, Valeri S. Gshalaev and Aleksandra C. DEMIRCHAN, 2012.
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
Midterm Examination150
Project Presentation250
SUM100
End Of Term (or Year) Learning ActivitiesQuantityWeight
Final Examination1100
SUM100
Term (or Year) Learning Activities50
End Of Term (or Year) Learning Activities50
SUM100
Language of Instruction
Turkish
Work Placement(s)
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination122
Final Examination122
Project Presentation288176
TOTAL WORKLOAD (hours)180
Contribution of Learning Outcomes to Programme Outcomes
LO1
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
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