| Course Unit Code | Course Unit Title | Type of Course Unit | Year of Study | Semester | Number of ECTS Credits | | OTİ-23-157 | Model OrganIsms Used In ToxIcologIcal Research | Elective | 1 | 3 | 6 |
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| Level of Course Unit |
| Second Cycle |
| Objectives of the Course |
| The aim of this course is to educate individuals who know the model organisms that can be used in toxicological researches and have knowledge about using these organisms. |
| Name of Lecturer(s) |
| Dr. Öğr. Üyesi Mine KÖKTÜRK |
| Learning Outcomes |
| 1 | Gains proficiency about model organisms | | 2 | Gains proficiency in model organisms used in toxicological studies and assays in which these model organisms are frequently used. | | 3 | Gains proficiency in model organisms with human homologous genes and the functions of some homologous genes | | 4 | Gains proficiency in model organisms, which are widely used in the study of the effects of toxic substances in developmental biology. |
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| Mode of Delivery |
| Daytime Class |
| Prerequisites and co-requisities |
| There is no prerequisite for this course. |
| Recommended Optional Programme Components |
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| Course Contents |
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| Weekly Detailed Course Contents |
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| 1 | Definition of model organism and general information | | | | 2 | Genetic Model Organisms | | | | 3 | Experimental Model Organisms | | | | 4 | Genomic Model Organisms | | | | 5 | Model organisms used in toxicological studies and analysis of these organisms frequently used | | | | 6 | Model organisms with homologous genes and functions of some homologous genes | | | | 7 | Model organisms commonly used to investigate the effects of toxic substances in developmental biology | | | | 8 | Mid-Term Exam | | | | 9 | Zebrafish and embryo / larvae as model organisms | | | | 10 | Using soil worms as model organisms | | | | 11 | Use of aquatic plants as a model organism (lemna minor) | | | | 12 | Use of Caenorhabditis elegans and mice as model organisms | | | | 13 | Use of Saccharomyces cerevisiae as a Model Organism | | | | 14 | Using Drosophila melanogaster as a Model Organism | | | | 15 | Final Exam | | |
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| Recommended or Required Reading |
| 1. Guille, M. (1999). Molecular Methods in Developmental Biology. Berlin: Springer.
2. Fründ, H. C., Butt, K., Capowiez, Y., Eisenhauer, N., Emmerling, C., Ernst, G., ... & Schrader, S. (2010). Using earthworms as model organisms in the laboratory: recommendations for experimental implementations. Pedobiologia, 53(2), 119-125.
3. Aliferis, K. A., Materzok, S., Paziotou, G. N., & Chrysayi-Tokousbalides, M. (2009). Lemna minor L. as a model organism for ecotoxicological studies performing 1H NMR fingerprinting. Chemosphere, 76(7), 967-973.
4. Hedges, S. B. (2002). The origin and evolution of model organisms. Nature Reviews Genetics, 3(11), 838. |
| Planned Learning Activities and Teaching Methods |
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| Assessment Methods and Criteria | |
| Midterm Examination | 1 | 100 | | SUM | 100 | |
| Final Examination | 1 | 100 | | SUM | 100 | | Term (or Year) Learning Activities | 50 | | End Of Term (or Year) Learning Activities | 50 | | SUM | 100 |
| | Language of Instruction | | | Work Placement(s) | |
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| Workload Calculation |
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| Attending Lectures | 15 | 2 | 30 |
| Discussion | 14 | 1 | 14 |
| Question-Answer | 14 | 1 | 14 |
| Criticising Paper | 14 | 1 | 14 |
| Self Study | 14 | 2 | 28 |
| Individual Study for Mid term Examination | 1 | 10 | 10 |
| Individual Study for Final Examination | 1 | 15 | 15 |
| Reading | 14 | 3 | 42 |
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| Contribution of Learning Outcomes to Programme Outcomes |
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| * Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High |
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Iğdır University, Iğdır / TURKEY • Tel (pbx): +90 476
226 13 14 • e-mail: info@igdir.edu.tr
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