Description of Individual Course Units
Course Unit CodeCourse Unit TitleType of Course UnitYear of StudySemesterNumber of ECTS Credits
TBİ-23-176ApplIcatIons of Response Surface Methodology In TIssue Culture Research Elective126
Level of Course Unit
Second Cycle
Objectives of the Course
The objectives of this course are: • to teach the basics of Response Surface Methodology (RSM) • to teach how to use RSM in tissue culture research
Name of Lecturer(s)
Doç.Dr.Melekşen AKIN
Learning Outcomes
1 The students will • learn the basics of RSM • learn how to apply RSM in tissue culture studies • learn how to generate RSM designs and analyze the data with RSM
Mode of Delivery
Daytime Class
Prerequisites and co-requisities
None
Recommended Optional Programme Components
Course Contents
Application of Response Surface Methodology in Tissue Culture Research
Weekly Detailed Course Contents
WeekTheoreticalPracticeLaboratory
1• Introduction to Response Surface Methods (RSM)
2• Factorial designs
3• Central Composite Design
4• Central Composite Design
5• Box-Behnken Design
6• Evaluating multiple responses
7• Evaluating multiple responses
8• Recap of the topics
9• Computer generated optimal design
10• Computer generated optimal design, data analyses and interpretation with RSM
11• Computer generated optimal design, data analyses and interpretation with RSM
12• Applying RSM to mixture design
13• Applying RSM to mixture design
14• Recap of the topics
Recommended or Required Reading
Akin, M., Eyduran, E., & Reed, B. M. (2016). Use of RSM and CHAID data mining algorithm for predicting mineral nutrition of hazelnut. Plant Cell, Tissue and Organ Culture, 128(2), 303-316. Anderson, M. J., & Whitcomb, P. J. (2005). RSM simplified: optimizing processes using response surface methods for design of experiments. New York, NY: Productivity Press. Niedz, R. P., & Evens, T. J. (2016). Design of experiments (DOE)—history, concepts, and relevance to in vitro culture. In Vitro Cellular & Developmental Biology - Plant, 52(6), 547–562.
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
Term (or Year) Learning ActivitiesQuantityWeight
Midterm Examination1100
SUM100
End Of Term (or Year) Learning ActivitiesQuantityWeight
Final Examination1100
SUM100
Term (or Year) Learning Activities40
End Of Term (or Year) Learning Activities60
SUM100
Language of Instruction
Work Placement(s)
Workload Calculation
ActivitiesNumberTime (hours)Total Work Load (hours)
Midterm Examination13030
Final Examination13030
Report Preparation13030
Project Preparation13030
Reading13030
Oral Examination13030
TOTAL WORKLOAD (hours)180
Contribution of Learning Outcomes to Programme Outcomes
PO
1
PO
2
PO
3
PO
4
PO
5
PO
6
LO1      
* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High
 
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