Course Unit Code | Course Unit Title | Type of Course Unit | Year of Study | Semester | Number of ECTS Credits | BMB-23-130 | Enzyme kInetIcs | Elective | 1 | 1 | 6 |
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Level of Course Unit |
Second Cycle |
Objectives of the Course |
To teach the basic lines of enzyme kinetics
To teach the structure, function, activity determination, inhibition and activation kinetics of enzymes for enzyme research. |
Name of Lecturer(s) |
Dr. Öğr. Üyesi Uğur GÜLLER |
Learning Outcomes |
1 | 1) Students are able to learn basic concepts of enzymes.
2) Students are able to learn the concepts of enzyme inhibition.
3) Students are able to learn graphs and equations related to enzyme kinetics.
4) Students are able to learn allosteric enzyme inhibition and kinetics.
5) Students are able to learn the types of enzyme inhibition. |
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Mode of Delivery |
Daytime Class |
Prerequisites and co-requisities |
none |
Recommended Optional Programme Components |
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Course Contents |
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Weekly Detailed Course Contents |
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1 | General information about proteins | | | 2 | Enzymes, general properties and purification criteria | | | 3 | Classification of enzymes | | | 4 | Enzyme cofactors | | | 5 | Coenzymes and enzyme active site | | | 6 | Enzyme inhibition-Michaelis Menten graph and obtaining the equation | | | 7 | Importance of KM and Vmax expressions | | | 8 | Enzyme inhibition-Eadie Hofstee graph, obtaining the equation, and interpretation | | | 9 | Wolf transformation | | | 10 | Kinetics of multi-substrate enzymatic reactions | | | 11 | Sterospecificity of enzymes and catalysis mechanism | | | 12 | Factors affecting enzyme activity | | | 13 | Multienzyme systems | | | 14 | Allosteric enzyme kinetics and inhibition | | |
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Recommended or Required Reading |
1) Biyokimya, E.Edip Keha ve Ö.İrfan Küfrevioğlu, Aktif Yayınevi, Erzurum, 2010.
2) Biyokimyanın İlkeleri, Albert L.Lehninger, David L.Nelson and Michael M.Cox, Second Edition, Worth Publishers, New York, 1993.
3) Biyokimya (Harper) Robert K. Murray, Daryl K. Granner, Peter A. Mayes, Victor W. Rodwell,Nobel Tıp Kitabevi, 2004.
4) Biyokimya , Pamela C. Champe, Richard A. Harvey, Denise R. Ferrier, Nobel Tıp Kitabevi,2007 |
Planned Learning Activities and Teaching Methods |
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Assessment Methods and Criteria | |
Midterm Examination | 1 | 100 | SUM | 100 | |
Final Examination | 1 | 100 | SUM | 100 | Term (or Year) Learning Activities | 50 | End Of Term (or Year) Learning Activities | 50 | SUM | 100 |
| Language of Instruction | Turkish | Work Placement(s) | |
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Workload Calculation |
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Midterm Examination | 1 | 1 | 1 |
Final Examination | 1 | 2 | 2 |
Attending Lectures | 14 | 3 | 42 |
Laboratory | 1 | 6 | 6 |
Problem Solving | 1 | 12 | 12 |
Discussion | 1 | 12 | 12 |
Experiment | 1 | 6 | 6 |
Brain Storming | 1 | 6 | 6 |
Report Preparation | 1 | 12 | 12 |
Report Presentation | 1 | 3 | 3 |
Project Preparation | 1 | 12 | 12 |
Project Presentation | 1 | 6 | 6 |
Seminar | 1 | 12 | 12 |
Criticising Paper | 1 | 12 | 12 |
Self Study | 1 | 12 | 12 |
Report | 1 | 12 | 12 |
Homework | 1 | 12 | 12 |
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Contribution of Learning Outcomes to Programme Outcomes |
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* Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High |
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Iğdır University, Iğdır / TURKEY • Tel (pbx): +90 476
226 13 14 • e-mail: info@igdir.edu.tr
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